
The episode must include at least 4 of the following 13 symptoms:
Palpitations, pounding heart, or accelerated heart rate
Sweating
Trembling or shaking
Shortness of breath or smothering sensations
Feelings of choking
Chest pain or discomfort
Nausea or abdominal distress
Dizziness, unsteadiness, lightheadedness, or faintness
Chills or heat sensations
Paresthesias (numbness or tingling sensations)
Derealization (feelings of unreality) or depersonalization (being detached from oneself)
Fear of losing control or “going crazy”
Fear of dying
A panic attack is not a mental disorder on its own. It is a specifier that can occur in the context of several disorders, including:
Panic Disorder
Social Anxiety Disorder
Specific Phobias
PTSD
Major Depressive Disorder
Substance/medication-induced conditions
Medical conditions
The DSM-5 describes two main types:
Expected (Cued) Panic Attacks
Occur in response to a known trigger (e.g., seeing a phobic object).
Unexpected (Uncued) Panic Attacks
Occur without an obvious trigger.
Unexpected, recurrent panic attacks are required for a diagnosis of Panic Disorder.
Panic Attack = A single episode of intense fear with physical symptoms.
Panic Disorder = Recurrent unexpected panic attacks plus at least one month of:
Persistent worry about additional attacks, or
Maladaptive behavioral changes related to the attacks (e.g., avoidance).
Psychotherapy (First-Line Treatment)
CBT is the most researched and effective treatment for panic attacks and panic disorder.
It helps by:
Identifying and challenging catastrophic thoughts (“I’m going to die”)
Reducing fear of bodily sensations
Teaching coping and breathing skills
Gradual exposure to feared sensations (interoceptive exposure)
Interoceptive exposure involves safely recreating physical sensations (e.g., spinning to induce dizziness) to reduce fear of them.
Most people see improvement within 8–16 sessions.
Used especially when panic attacks are linked to avoidance (e.g., driving, crowded places). Gradual exposure reduces fear over time.
Focuses on accepting anxiety symptoms instead of fighting them and committing to valued actions.
Medication may be recommended when:
Panic attacks are frequent or severe
Therapy alone isn’t enough
There is significant functional impairment
Sertraline
Fluoxetine
Paroxetine
Escitalopram
These regulate serotonin and reduce panic frequency over time.
Effects usually begin in 2–6 weeks.
Venlafaxine (FDA-approved for panic disorder)
Alprazolam
Lorazepam
Clonazepam
They act quickly but carry risks:
Dependence
Tolerance
Withdrawal symptoms
Typically used short-term or in specific cases.
Tricyclic antidepressants (e.g., imipramine)
Beta-blockers (sometimes used for physical symptoms) like Propranolol, Metoprolol
Alpha-Blocker like Clonidine
Anti-histamine like Hydroxyzine
Gabapentin
Buspar
Second generation antipsychotic like Seroquel, Haldol
These are supportive but often helpful alongside therapy:
Slow diaphragmatic breathing helps regulate hyperventilation.
Example:
Inhale for 4 seconds
Hold for 4 seconds
Exhale for 6 seconds
5-4-3-2-1 sensory exercise
Naming objects in the room
Cold water on wrists
Limit caffeine
Reduce alcohol
Avoid recreational drugs
Maintain regular sleep
Improves stress regulation and reduces anxiety sensitivity.